SIGN2023EN
SIGN 146: Cutaneous melanoma
Zusammenfassung
Cutaneous melanoma
A national clinical guideline
First published January 2017
Revised August 2023
Revised February 2025
SIGN14 6
Key to evidence statements and recommendations
Levels of evidence
1
++
High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias
1
+
Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias
1
–
Meta-analyses, systematic reviews, or RCTs with a high risk of bias
2
++
High-quality syste
Kerninformationen
R For ‘conditional’ recommendations on interventions that should be ‘considered’, the guideline development
group is confident that the intervention will do more good than harm for most patients. The choice of
intervention is therefore more likely to vary depending on a person’s values and prefere...
Cutaneous melanoma 2025. (SIGN publication no. 146). [February 2025]. Available from URL: http://www.sign.ac.uk
This document is licensed under the Creative Commons Attribution-Noncommercial-NoDerivatives
4.0 International Licence. This allows for the copy and redistribution of this document as lon...
In Scotland it is the fifth most common cancer in women and
seventh in men.
1
In Scotland, between 2007 and 2018, the incidence of melanoma in adults has
increased by 6%, but mortality rates have decreased by 10–19.1% between 2008 and 2018.
1
The primary risk factor for cutaneous melanoma is ex...
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