Diabetes Canada Chapter 3: Definition, Classification and Diagnosis of Diabetes, Prediabetes and Metabolic Syndrome

Zusammenfassung

KEY MESSAGES: Key Messages The chronic hyperglycemia of diabetes is associated with significant long-term microvascular and cardiovascular complications. A fasting plasma glucose of >=7.0 mmol/L, a 2-hour plasma glucose value in a 75 g oral glucose tolerance test of >=11.1 mmol/L or a glycated hemoglobin (A1C) of >=6.5% can predict the development of retinopathy. This permits the diagnosis of diabetes to be made on the basis of each of these parameters. The term "prediabetes" refers to impaired

Kerninformationen

e insulin action or both. The chronic hyperglycemia of diabetes is associated with relatively specific long-term microvascular complications affecting the eyes, kidneys and nerves, as well as an increased risk for cardiovascular disease (CVD). The diagnostic criteria for diabetes are based on thresh...

s and monogenic diabetes. No diagnostic test or clinical criteria can reliably make this distinction, but additional testing may be helpful in atypical presentations if knowing the specific diagnosis may alter management. One monogenic form to highlight is neonatal diabetes, which typically presents...

ee Appendix 2 . Etiologic Classification of Diabetes Mellitus). Obesity and physical signs of insulin resistance (e.g. acanthosis nigricans) are more common in children and adolescents with type 2 diabetes than type 1 diabetes. In adults, a systematic review of clinical indicators identified age at ...

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