Diabetes Canada Chapter 29: Chronic Kidney Disease in Diabetes

Zusammenfassung

KEY MESSAGES: Key Messages Identification of chronic kidney disease in people with diabetes requires screening for proteinuria, as well as an assessment of serum creatinine converted into an estimated glomerular function rate (eGFR). All individuals with chronic kidney disease should be considered at high risk for cardiovascular events and should be treated to reduce these risks. The development and progression of renal damage in diabetes can be reduced and slowed through intensive glycemic cont

Kerninformationen

a low-potassium diet. If persistent, non-potassium-sparing diuretics and/or oral sodium bicarbonate (in those with a metabolic acidosis) should be considered. Consider temporarily reducing or holding RAAS blockade (i.e. ACE inhibitor, ARB or DRI). Severe hyperkalemia: In addition to emergency manage...

rly thereafter [Grade D, Consensus]. A diagnosis of CKD should be made in people with an eGFR <60 mL/min/1.73 m 2 and/or random urine ACR >=2.0 mg/mmol on at least 2 of 3 samples over a 3-month period [Grade D, Consensus]. All people with diabetes and CKD should receive a comprehensive, multifaceted...

BP. In adults with type 2 diabetes with clinical CVD in whom glycemic targets are not achieved with existing antihyperglycemic medication(s) and with an eGFR >30 mL/min/1.73 m 2 , an SGLT2 inhibitor with proven renal benefit may be considered to reduce the risk of progression of nephropathy [Grade B...

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