DrugBank: Omeprazole - Pharmacological Profile

Zusammenfassung

DRUGBANK PHARMACOLOGICAL PROFILE: Omeprazole Drug Class: Proton pump inhibitor (PPI) Category: Gastrointestinal === MECHANISM OF ACTION === Irreversibly inhibits gastric H+/K+-ATPase. First PPI developed. Reduces acid secretion by up to 95%. Inactive at neutral pH, activated in acidic canaliculus. === INDICATIONS === - GERD - Peptic ulcer disease - H. pylori eradication - Zollinger-Ellison syndrome - NSAID-induced ulcer prevention === CONTRAINDICATIONS === - Hypersensitivity - Concomitant ri

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