Cochrane2023IaEN
Cochrane Review: Tourniquet use for people with peripheral arterial disease undergoing major lower limb amputations
Zusammenfassung
# Tourniquet use for people with peripheral arterial disease undergoing major lower limb amputations.
## BACKGROUND
At least 7000 major lower limb amputations (MLLAs) are performed in the UK each year, 80% of which are due to peripheral arterial disease (PAD). Intraoperative blood loss can have a deleterious effect on patient outcomes, and its replacement with transfused blood is not without risk. Tourniquets can be used in lower limb surgical procedures to provide a bloodless surgical field,
Kerninformationen
ly compromising perfusion of the stump and thereby impacting wound healing through direct tissue injury, damage to the arterial supply of the wound, or both.
## OBJECTIVES
To assess the safety and effectiveness of tourniquet use in people undergoing MLLA for complications of PAD, specifically with...
controlled trials (RCTs) comparing tourniquet use to no tourniquet use among people with PAD undergoing MLLA.
## DATA COLLECTION AND ANALYSIS
We used standard Cochrane methods. Primary outcomes were intraoperative blood loss, fall in haemoglobin levels, and perioperative blood transfusion require...
n for non-reconstructable PAD were randomised to either tourniquet or no tourniquet to assess for intraoperative blood loss, fall in haemoglobin, transfusion requirement, wound healing, stump breakdown and revision. Ten participants were excluded postrandomisation (five from the tourniquet group and...
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