Cochrane Review: Oral vitamin D supplementation for adults with obesity undergoing bariatric surgery

Zusammenfassung

# Oral vitamin D supplementation for adults with obesity undergoing bariatric surgery. ## BACKGROUND Vitamin D deficiency following bariatric surgery is common and is expected to be associated with a deleterious impact on the skeleton. However, the benefits of vitamin D supplementation and the optimal dose in this population is currently unknown. The available guidelines on the topic are derived from experts' opinions, and are not evidence based. ## OBJECTIVES To compare the effects of diffe

Kerninformationen

TRAL, MEDLINE, Embase, LILACS, two trial registries, and the reference lists of systematic reviews, articles, and health technology assessment reports without language restrictions. The last search of all databases was 27 June 2023, except Embase, which we searched on 14 August 2015. ## SELECTION C...

used GRADE to assess the certainty of the evidence for each outcome in each comparison. ## MAIN RESULTS We identified five trials with 314 participants. We included three trials in the quantitative analysis. Moderate-dose vitamin D compared to placebo One trial compared moderate-dose vitamin D (3...

d not provide any information on adverse events in the placebo arm. There were no data on fractures, all-cause mortality, bone density change, health-related quality of life, and muscle strength. High-dose vitamin D compared to moderate-dose vitamin D Two trials in Roux-en-Y gastric bypass compared ...

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