DrugBank: Tramadol - Pharmacological Profile

Zusammenfassung

DRUGBANK PHARMACOLOGICAL PROFILE: Tramadol Drug Class: Centrally-acting atypical opioid analgesic Category: Pain/Musculoskeletal === MECHANISM OF ACTION === Dual mechanism: weak mu-opioid receptor agonist AND serotonin/norepinephrine reuptake inhibitor. Active metabolite O-desmethyltramadol (M1) has 200x higher mu-affinity than parent. CYP2D6-dependent activation. === INDICATIONS === - Moderate to moderately severe pain - Post-operative pain - Chronic pain (extended-release) - Neuropathic pai

Fragen zu diesem Thema?

ClariMed durchsucht alle Leitlinien mit KI und liefert quellenbasierte Antworten in Sekunden.

Jetzt auf ClariMed suchen