Cochrane Review: Corticosteroids as standalone or add-on treatment for sore throat

Zusammenfassung

# Corticosteroids as standalone or add-on treatment for sore throat. ## BACKGROUND Sore throat is a common condition associated with a high rate of antibiotic prescriptions, despite limited evidence for the effectiveness of antibiotics. Corticosteroids may improve symptoms of sore throat by reducing inflammation of the upper respiratory tract. This review is an update to our review published in 2012. ## OBJECTIVES To assess the clinical benefit and safety of corticosteroids in reducing the s

Kerninformationen

also searched the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) and ClinicalTrials.gov. ## SELECTION CRITERIA We included randomised controlled trials (RCTs) that compared steroids to either placebo or standard care in adults and children (aged over three ye...

and placebo groups received antibiotics; one trial offered delayed prescription of antibiotics based on clinical assessment. Only two trials reported funding sources (government and a university foundation). In addition to any effect of antibiotics and analgesia, corticosteroids increased the likel...

pain by 6 and 11.6 hours, respectively, although significant heterogeneity was present (moderate-certainty evidence). At 24 hours, pain (assessed by visual analogue scales) was reduced by an additional 10.6% by corticosteroids (moderate-certainty evidence). No differences were reported in recurrence...

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