Cochrane Review: Non-invasive positive pressure ventilation for central sleep apnoea in adults

Zusammenfassung

# Non-invasive positive pressure ventilation for central sleep apnoea in adults. ## BACKGROUND Central sleep apnoea (CSA) is characterised by abnormal patterns of ventilation during sleep due to a dysfunctional drive to breathe. Consequently, people with CSA may present poor sleep quality, sleep fragmentation, inattention, fatigue, daytime sleepiness, and reduced quality of life. ## OBJECTIVES To assess the effectiveness and safety of non-invasive positive pressure ventilation (NIPV) for the

Kerninformationen

studies, and scanned the reference lists of included studies to identify additional studies. ## SELECTION CRITERIA We included randomised controlled trials (RCTs) reported in full text, those published as abstract only, and unpublished data. ## DATA COLLECTION AND ANALYSIS Two review authors in...

risk of bias for at least one domain, and all studies as at unclear risk of bias for at least two domains. The trials included participants aged > 18 years old, of which 70% to 100% were men, who were followed from one week to 60 months. The included studies assessed the effects of different modes o...

e short term, CPAP plus best supportive care may reduce central apnoea hypopnoea index (AHI) (mean difference (MD) -14.60, 95% confidence interval (CI) -20.11 to -9.09; 1 study; 205 participants). However, CPAP plus best supportive care may result in little to no difference in cardiovascular mortali...

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