Cochrane2025IaEN
Cochrane Review: Brexanolone, zuranolone and related neurosteroid GABA(A) receptor positive allosteric modulators for postnatal depression
Zusammenfassung
Brexanolon, Zuranolon und verwandte positive allosterische Modulatoren von Neurosteroiden am GABA A ‐Rezeptor zur Behandlung postnataler Depressionen - Wilson, CA - 2025 \| Cochrane Library
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[Cochrane Database of Systematic reviews](https://www.cochranelibrary.com/en/about/about-cochrane-reviews) Review - Intervention
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## Abstract
available in
### Background
Postnatal depression – depression that occur...
of depression, including postnatal depression, and have a different mechanism of action than traditional antidepressants.
### Objectives
To assess the benefits and harms of brexanolone, zuranolone and related neurosteroid GABAA receptor positive allosteric modulators compared to another active tr...
during the first 12 months following childbirth that compared neurosteroid GABAA receptor positive allosteric modulators with any other treatment (pharmacological, psychological or psychosocial), placebo or treatment as usual.
### Data collection and analysis
We used standard Cochrane methodologi...
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