Cochrane2019IaEN
Cochrane Review: Prostacyclin for pulmonary arterial hypertension
Zusammenfassung
Prostacyclin zur Behandlung der pulmonalen Hypertonie - Barnes, H - 2019 \| Cochrane Library
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Kerninformationen
](https://www.cochranelibrary.com/en/about/about-cochrane-reviews) Review - Intervention
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## Abstract
available in
### Background
Pulmonary arterial hypertension (PAH) is characterised by pulmonary vascular changes, leads to elevated pulmonary artery pressures, dyspnoea,...
sk of adverse events. Newer and safer subcutaneous, oral and inhaled preparations are now available, though possibly less potent.
Selexipag is an oral selective prostacyclin receptor (IP receptor) agonist that works similarly to prostacyclin, potentially more stable, with less complex administratio...
nalogues or prostacyclin receptor agonists to control (placebo, any other treatment or usual care) for at least six weeks.
### Data collection and analysis
We used standard methods specified by Cochrane. Primary outcomes included change in World Health Organization (WHO) functional class, six‐minu...
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