DrugBank: Enoxaparin - Pharmacological Profile

Zusammenfassung

DRUGBANK PHARMACOLOGICAL PROFILE: Enoxaparin Drug Class: Low molecular weight heparin (LMWH) Category: Cardiovascular === MECHANISM OF ACTION === Binds antithrombin III, enhancing its inhibition of Factor Xa (primary) and thrombin (secondary, less than UFH). More predictable dose-response than unfractionated heparin. Anti-Xa:anti-IIa ratio ~3.8:1. === INDICATIONS === - VTE prophylaxis (surgical/medical patients) - DVT/PE treatment - Acute coronary syndrome - Bridge therapy for VKA/procedures

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