Diabetes Canada Chapter 28: Treatment of Diabetes in People with Heart Failure

Zusammenfassung

KEY MESSAGES: Key Messages Heart failure is still under-recognized and misdiagnosed. This has significant clinical implications as the prognosis of untreated or undertreated heart failure is poor, and yet very effective proven therapies are widely available to most. Diabetes can cause heart failure independently of ischemic heart disease by causing a diabetic cardiomyopathy that may manifest in the setting of normal or reduced left ventricular ejection fraction. The incidence of heart failure is

Kerninformationen

Introduction Type 2 diabetes often occurs in association with other cardiovascular (CV) risk factors, such as hypertension, dyslipidemia, smoking and obesity, which, together, are strongly associated with atherosclerosis, ischemic heart disease and left ventricular (LV) dysfunction (1) . LV dysfunct...

e proven therapies are widely available. Because of this, many studies have explored the clinical utility of screening people with diabetes for the presence of reduced LV function with BNP/NT-pro- BNP testing. The results to date are mixed, with no clear consensus to institute this strategy. A recen...

r systolic and diastolic function, independently from ischemic heart disease or systemic hypertension. While an increase in glycated hemoglobin (A1C) among individuals with diabetes is a recognized risk factor for heart failure (8-12) , no prospective study to date has demonstrated that improved gly...

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