Cochrane Review: Surgery for nasal polyposis in cystic fibrosis

Zusammenfassung

# Surgery for nasal polyposis in cystic fibrosis. ## BACKGROUND Cystic fibrosis (CF) is a life-shortening, autosomal recessive disease that leads to abnormal electrolyte concentration in exocrine secretions. Secretion stasis in paranasal sinuses determines chronic rhinosinusitis (CRS) and nasal polyposis. Endoscopic sinus surgery is used to open the sinuses and allow medical treatment to work properly. ## OBJECTIVES To determine the effects of sinus surgery alone or in combination with medic

Kerninformationen

tics and pulmonary exacerbation rates. ## SEARCH METHODS We searched the Cochrane Cystic Fibrosis Trials Register, compiled from electronic database searches and hand searching of journals and conference abstract books. Date of last search: 4 July 2022. We also searched other databases (Pubmed, Em...

e evidence using GRADE. They contacted the authors of the included study for additional information. ## MAIN RESULTS We identified 66 publications relating to 50 studies from electronic searches. Only one study fulfilled the inclusion criteria, and only limited information was available. In this s...

in whether the addition of surgery to medical treatment leads to changes in pulmonary function. There was one episode of bleeding during surgery that was corrected during the procedure with no further consequences. The study did not report on survival. ## AUTHORS' CONCLUSIONS Very low-certainty ev...

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