IDSA2009EN
AASLD: Hepatitis B (2009)
Zusammenfassung
AASLD PRACTICE GUIDELINE UPDATE
Chronic Hepatitis B: Update 2009
Anna S. F. Lok
1
and Brian J. McMahon
2
The 2009 update of the American Association for the
Study of Liver Diseases (AASLD) Practice Guidelines
for Management of Chronic Hepatitis B are now
posted online at www.aasld.org. This is the fourth ver-
sion of this guideline; the last version was published in
2007.
1
The key changes in the 2009 version are new recom-
mendations for first-line and second-line antiviral
agents. Since the
Kerninformationen
ose who
remained viremic at week 72—received additional
therapy with emtricitabine. Therefore, data on resis-
tance to tenofovir monotherapy beyond 72 weeks can-
not be determined from the two pivotal trials. The
primary resistance mutation has not been determined.
An alanine-to-threonine substituti...
l be receiv-
ing cancer chemotherapy or long-term immunosuppres-
sive therapy. Please refer to recommendations 1 and 39,
and table 2.
References
1. Lok ASF, McMahon BJ. Chronic hepatitis B. HEPATOLOGY2007;45:507-
539.
Abbreviations: HBeAg, hepatitis B e antigen; HBV, hepatitis B virus; HIV,
human im...
coni syndrome and renal failure induced by tenofovir: a first
case report. Am J Kidney Dis 2002;40:1331-1333.
5. Sasadeusz J, Audsley J, Mijch A, Baden R, Caro J, Hunter H, et al.
The anti-HIV activity of entecavir: a multicentre evaluation of lamivu-
dine-experienced and lamivudine-naive patients. ...
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