Cochrane Review: Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery

Zusammenfassung

# Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery. ## BACKGROUND Concerns regarding the safety and availability of transfused donor blood have prompted research into a range of techniques to minimise allogeneic transfusion requirements. Cell salvage (CS) describes the recovery of blood from the surgical field, either during or after surgery, for reinfusion back to the patient. ## OBJECTIVES To examine the effectiveness of CS in min

Kerninformationen

d systematic reviews from 2009 (date of previous search) to 19 January 2023, without restrictions on language or publication status. ## SELECTION CRITERIA We included RCTs assessing the use of CS compared to no CS in adults (participants aged 18 or over, or using the study's definition of adult) u...

high certainty. Reasons for downgrading the certainty included imprecision (small sample sizes below the optimal information size required to detect a difference, and wide confidence intervals), inconsistency (high statistical heterogeneity), and risk of bias (high risk from domains including seque...

thrombosis (DVT). There were no analysable data reported for the remaining outcomes. Cardiovascular (vascular): 6 RCTs (384 participants) Very low- to low-certainty evidence means we are uncertain whether there is a difference for most outcomes. No data were reported for major adverse cardiovascula...

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